There is a whole 'nother level of safety validation that goes beyond your everyday OWASP, or heck even what we consider "highly regulated" industry requirements that 95-99% of us devs care about. SQLite is used in some highly specialized, highly sensitive environments, where they are concerned about bit flips, and corrupted memory. I had the luxury of sitting through Richard Hipp's talk about it one time, but I am certainly butchering it.