Also consider that we, the Earthbound humans, will probably never live comfortably in space, or low gravity environments. We're just not built for it and there are many physiological issues we'd face.
That of course doesn't mean humans never will, future generations, should they go to space, will adapt and evolve to their new environments, whether naturally or through deliberate selection. You and I, we never will. But our descendants might.
I suspect if our 'civilisation' continued long enough to do serious manned space exploration, low gravity is an issue we'd find a technical fix for. Your guess is as good as mine though.
It's pretty clear however that we're unlikely to make it that far.
That of course doesn't mean humans never will, future generations, should they go to space, will adapt and evolve to their new environments, whether naturally or through deliberate selection. You and I, we never will. But our descendants might.